Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/294872992?client_source=feed&format=rss
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বৃহস্পতিবার, ২৮ মার্চ, ২০১৩
Pop-up Gmail compose now default whether you like it or not
When Google soft launched its new Gmail composer last October, it did so in a preview release that gave users the option to test it out and turn it off. Not so anymore, because starting today that resizable, pop-up window is now the default interface for its web Gmail client. The widespread change was apparently spurred by abundant positive feedback from users that found the new layout bolstered multitasking -- a claim we're not entirely sold on. Regardless of your feelings towards this permanent switch, it's headed your way soon and should finish rolling out "over the next few days." So, turn and face the change, people -- it's not like you have a choice.
Source: Official Gmail Blog
Source: http://www.engadget.com/2013/03/28/pop-up-gmail-compose-now-default/
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বুধবার, ২৭ মার্চ, ২০১৩
What a bunch of dodos! A catastrophic mass extinction of birds in the Pacific Islands followed the arrival of the first people
Mar. 25, 2013 ? Research carried out by the Zoological Society of London (ZSL) and collaborators reveals that the last region on earth to be colonised by humans was home to more than 1,000 species of birds that went extinct soon after people reached their island homes.
The paper was published today (March 25th) in the journal Proceedings of the National Academy of Sciences.
Almost 4,000 years ago, tropical Pacific Islands were an untouched paradise, but the arrival of the first people in places like Hawaii and Fiji caused irreversible damage to these natural havens, due to overhunting and deforestation. As a result, birds disappeared. But understanding the scale and extent of these extinctions has been hampered by uncertainties in the fossil record.
Professor Tim Blackburn, Director of ZSL's Institute of Zoology says: "We studied fossils from 41 tropical Pacific islands and using new techniques we were able to gauge how many extra species of bird disappeared without leaving any trace."
They found that 160 species of non-passerine land birds (non-perching birds which generally have feet designed for specific functions, for example webbed for swimming) went extinct without a trace after the first humans arrived on these islands alone.
"If we take into account all the other islands in the tropical Pacific, as well as seabirds and songbirds, the total extinction toll is likely to have been around 1,300 bird species," Professor Blackburn added.
Species lost include several species of moa-nalos, large flightless waterfowl from Hawai'i, and the New Caledonian Sylviornis, a relative of the game birds (pheasants, grouse, etc) but which weighed in at around 30kg, three times as heavy as a swan.
Certain islands and bird species were particularly vulnerable to hunting and habitat destruction. Small, dry islands lost more species because they were more easily deforested and had fewer places for birds to hide from hunters. Flightless birds were over 30 times more likely to become extinct that those that could fly.
Bird extinctions in the tropical Pacific did not stop with these losses. Forty more species disappeared after Europeans arrived, and many more species are still threatened with extinction today.
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The above story is reprinted from materials provided by Zoological Society of London, via EurekAlert!, a service of AAAS.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Richard P. Duncan, Alison G. Boyer, and Tim M. Blackburn. Magnitude and variation of prehistoric bird extinctions in the Pacific. PNAS, March 25, 2013 DOI: 10.1073/pnas.1216511110
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
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Counting white blood cells at home
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Public release date: 26-Mar-2013[ | E-mail |
Share ] Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology
Caltech engineers lead development of a new portable counter
PASADENA, Calif.White blood cells, or leukocytes, are the immune system's warriors. So when an infection or disease attacks the body, the system typically responds by sending more white blood cells into the fray. This means that checking the number of these cells is a relatively easy way to detect and monitor such conditions.
Currently, most white blood cell counts are performed with large-scale equipment in central clinical laboratories. If a physician collects blood samples from a patient in the officeusually requiring a full vial of blood for each testit can take days to get the results. But now engineers at the California Institute of Technology (Caltech), working with a collaborator from the Jerusalem-based company LeukoDx, have developed a portable device to count white blood cells that needs less than a pinprick's worth of blood and takes just minutes to run.
"The white blood cell counts from our new system closely match the results from tests conducted in hospitals and other central clinical settings," says Yu-Chong Tai, professor of electrical engineering and mechanical engineering at Caltech and the project's principal investigator. "This could make point-of-care testing possible for the first time."
Portable white blood cell counters could improve outpatient monitoring of patients with chronic conditions such as leukemia or other cancers. The counters could be used in combination with telemedicine to bring medical care to remote areas. The devices could even enable astronauts to evaluate their long-term exposure to radiation while they are still in space. The researchers describe the work in the April 7 issue of the journal Lab on a Chip.
There are five subtypes of white blood cells, and each serves a different function, which means it's useful to know the count for all of them. In general, lymphocytes use antibodies to attack certain viruses and bacteria; neutrophils are especially good at combating bacteria; eosinophils target parasites and certain infections; monocytes respond to inflammation and replenish white blood cells within bodily tissue; and basophils, the rarest of the subtypes, attack certain parasites.
"If we can give you a quick white blood cell count right in the doctor's office," says Wendian Shi, a graduate student in Tai's lab and lead author of the new paper, "you can know right away if you're dealing with a viral infection or a bacterial infection, and the doctor can prescribe the right medication."
The prototype device is able to count all five subtypes of white blood cells within a sample. It provides an accurate differential of the four major subtypeslymphocytes, monocytes, eosinophils, and neutrophils. In addition, it could be used to flag an abnormally high level of the fifth subtype, basophils, which are normally too rare (representing less than one percent of all white blood cells) for accurate detection in clinical tests.
The entire new system fits in a small suitcase (12" x 9" x 5") and could easily be made into a handheld device, the engineers say.
A major development reported in the new paper is the creation of a detection assay that uses three dyes to stain white blood cells so that they emit light, or fluoresce, brightly in response to laser light. Blood samples are treated with this dye assay before measurement in the new device. The first dye binds strongly to the DNA found in the nucleus of white blood cells, making it simple to distinguish between white blood cells and the red blood cells that surround and outnumber them. The other two dyes help differentiate between the subtypes.
The heart of the new device is a 50-micrometer-long transparent channel made out of a silicone material with a cross section of only 32 micrometers by 28 micrometerssmall enough to ensure that only one white blood cell at a time can flow through the detection region. The stained blood sample flows through this microfluidic channel to the detection region, where it is illuminated with a laser, causing it to fluoresce. The resulting emission of the sample is then split by a mirror into two beams, representing the green and red fluorescence.
Thanks to the dye assay, the white blood cell subtypes emit characteristic amounts of red and green light. Therefore, by determining the intensity of the emissions for each detected cell, the device can generate highly accurate differential white blood cell counts.
Shi says his ultimate goal is to develop a portable device that can help patients living with chronic diseases at home. "For these patients, who struggle to find a balance between their treatment and their normal quality of life, we would like to offer a device that will help them monitor their conditions at home," he says. "It would be nice to limit the number of trips they need to make to the hospital for testing."
###
The Lab on a Chip paper is titled "Four-part leukocyte differential count based on sheathless microflow cytometer and fluorescent dye assay." In addition to Tai and Shi, the coauthors on the paper are Luke Guo, a graduate student at MIT who worked on the project as an undergraduate student at Caltech, and Harvey Kasdan of LeukoDx Inc. in Jerusalem, Israel. The work was supported by the National Space Biomedical Research Institute under a NASA contract.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 26-Mar-2013[ | E-mail |
Share ] Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology
Caltech engineers lead development of a new portable counter
PASADENA, Calif.White blood cells, or leukocytes, are the immune system's warriors. So when an infection or disease attacks the body, the system typically responds by sending more white blood cells into the fray. This means that checking the number of these cells is a relatively easy way to detect and monitor such conditions.
Currently, most white blood cell counts are performed with large-scale equipment in central clinical laboratories. If a physician collects blood samples from a patient in the officeusually requiring a full vial of blood for each testit can take days to get the results. But now engineers at the California Institute of Technology (Caltech), working with a collaborator from the Jerusalem-based company LeukoDx, have developed a portable device to count white blood cells that needs less than a pinprick's worth of blood and takes just minutes to run.
"The white blood cell counts from our new system closely match the results from tests conducted in hospitals and other central clinical settings," says Yu-Chong Tai, professor of electrical engineering and mechanical engineering at Caltech and the project's principal investigator. "This could make point-of-care testing possible for the first time."
Portable white blood cell counters could improve outpatient monitoring of patients with chronic conditions such as leukemia or other cancers. The counters could be used in combination with telemedicine to bring medical care to remote areas. The devices could even enable astronauts to evaluate their long-term exposure to radiation while they are still in space. The researchers describe the work in the April 7 issue of the journal Lab on a Chip.
There are five subtypes of white blood cells, and each serves a different function, which means it's useful to know the count for all of them. In general, lymphocytes use antibodies to attack certain viruses and bacteria; neutrophils are especially good at combating bacteria; eosinophils target parasites and certain infections; monocytes respond to inflammation and replenish white blood cells within bodily tissue; and basophils, the rarest of the subtypes, attack certain parasites.
"If we can give you a quick white blood cell count right in the doctor's office," says Wendian Shi, a graduate student in Tai's lab and lead author of the new paper, "you can know right away if you're dealing with a viral infection or a bacterial infection, and the doctor can prescribe the right medication."
The prototype device is able to count all five subtypes of white blood cells within a sample. It provides an accurate differential of the four major subtypeslymphocytes, monocytes, eosinophils, and neutrophils. In addition, it could be used to flag an abnormally high level of the fifth subtype, basophils, which are normally too rare (representing less than one percent of all white blood cells) for accurate detection in clinical tests.
The entire new system fits in a small suitcase (12" x 9" x 5") and could easily be made into a handheld device, the engineers say.
A major development reported in the new paper is the creation of a detection assay that uses three dyes to stain white blood cells so that they emit light, or fluoresce, brightly in response to laser light. Blood samples are treated with this dye assay before measurement in the new device. The first dye binds strongly to the DNA found in the nucleus of white blood cells, making it simple to distinguish between white blood cells and the red blood cells that surround and outnumber them. The other two dyes help differentiate between the subtypes.
The heart of the new device is a 50-micrometer-long transparent channel made out of a silicone material with a cross section of only 32 micrometers by 28 micrometerssmall enough to ensure that only one white blood cell at a time can flow through the detection region. The stained blood sample flows through this microfluidic channel to the detection region, where it is illuminated with a laser, causing it to fluoresce. The resulting emission of the sample is then split by a mirror into two beams, representing the green and red fluorescence.
Thanks to the dye assay, the white blood cell subtypes emit characteristic amounts of red and green light. Therefore, by determining the intensity of the emissions for each detected cell, the device can generate highly accurate differential white blood cell counts.
Shi says his ultimate goal is to develop a portable device that can help patients living with chronic diseases at home. "For these patients, who struggle to find a balance between their treatment and their normal quality of life, we would like to offer a device that will help them monitor their conditions at home," he says. "It would be nice to limit the number of trips they need to make to the hospital for testing."
###
The Lab on a Chip paper is titled "Four-part leukocyte differential count based on sheathless microflow cytometer and fluorescent dye assay." In addition to Tai and Shi, the coauthors on the paper are Luke Guo, a graduate student at MIT who worked on the project as an undergraduate student at Caltech, and Harvey Kasdan of LeukoDx Inc. in Jerusalem, Israel. The work was supported by the National Space Biomedical Research Institute under a NASA contract.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-03/ciot-cwb032513.php
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Listing Fail: Even 'Ugly' Homes Need Buyers | AOL Real Estate
We agree that honesty is the best policy in life, love and, yes, listings. But although mama might not have told you so, a little white lie never hurt anyone. Well, at least not being so bluntly honest.
You wouldn't tell your date that you'd prefer she wear more makeup next time, would you? (Even if she is ugly as sin.) Same goes for listings: You don't have to make it so blatantly obvious that the house you're selling is unattractive as hell. Quite frankly, if it's that ugly, then maybe you shouldn't be showing photos of it in the first place.
Here's a case in point: This listing (pictured above) in Toledo, Ill., minces no words about how devastatingly ugly it is. The listing reads: "Exterior my look like ugly duckling." (The only thing uglier? The spelling and grammar.) The owner does add as an afterthought: "Inside fixed up nice." Um, thanks. It's what's on the inside that matters, right?
Similarly, this listing in Warren, Ill. (pictured above), cuts right to the chase. Its headline reads: "Ugly. Outdated." (Complete with check marks.) Even though the owner later concedes that the home has "tons of potential," we've already checked this one off our list.
Over in Kansas City, Mo., this home is so ugly that the owner can't even show a picture of it! The owner explains, "The outside is very ugly until i get a chance to paint in spring." But the listing adds that it's been remodeled with new floors, and "you have to see it!!" Nah, we'll wait until spring -- if we haven't found another home by then.
Enjoy this post? Check out all our listing fail articles!
See also:
Spring Home Makeover Don'ts: HGTV's Sabrina Soto On Big Mistakes
Extreme Home Makeovers: From Sorry to Stunning
Quick and Easy Home Makeovers
More on AOL Real Estate:
Find out how to calculate mortgage payments.
Find homes for sale in your area.
Find foreclosures in your area.
See celebrity real estate.
Source: http://realestate.aol.com/blog/2013/03/25/selling-ugly-house-listing-fail/
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Who?s who in the Prop 8 gay marriage case
On Tuesday morning, the Supreme Court hears oral arguments in the first gay marriage case to ever reach the court, Hollingsworth v. Perry.
The legal battle over California's gay marriage ban began more than four years ago, when a majority of voters backed ballot Proposition 8, which rescinded the right to marry from same-sex couples.
Since then, Prop 8 has been struck down by both a district and federal appeals court as discriminatory, and along the way lost its main legal defender: the government of California. After the district court decision, then-Governor Arnold Schwarzenegger declined to appeal the case further, leaving a coalition of Prop 8 supporters led by a a former state senator to take up the cause.
The Supreme Court could use the case to issue a broad ruling guaranteeing the right to marriage to same-sex couples--or to shut down gay rights advocates' claims of wrongful exclusion from the institution of marriage altogether. The court also may issue a ruling in between these extremes.
As both sides prepare to argue their cause, we take a look at some of the major faces behind the high-profile case.
The plaintiffs:
Two unmarried same-sex couples in California were handpicked by the well-financed campaign against Prop 8 to challenge the gay marriage ban as discriminatory.
Kris Perry, whose last name is featured in the Hollingsworth v Perry case name, and Sandy Stier married in 2004 in San Francisco, but the state Supreme Court invalidated that marriage only six months later.
They have been together for 13 years, and raised four sons together from previous relationships. Perry, 48, told the Associated Press that ?we've lived our lives in this hurry-up-and-wait, pins-and-needles way,? since the case began four years ago.
Paul Katami and Jeff Zarrillo of Burbank, Calif., also were chosen as plaintiffs after gay rights advocates noticed a YouTube video Katami helped make to respond to gay marriage critics called, ?Weathering the Storm.? A lawyer involved in the case told The Washington Post that they approached ?several couples? about whether they would be interested in in being plaintiffs in the high profile challenge to Prop 8, warning them that their lives could face extra scrutiny if they accepted.
"We honestly think of ourselves as kind of regular, everyday guys," Katami told USA Today. "We're not asking for a special right."
Katami and Zarrillo have been together for 12 years, and hope to get married and have children if their case is successful.
Their attorneys:
The two same-sex couples are represented by Theodore Olson, the former Solicitor General under George W. Bush, and David Boies, a high profile Democratic lawyer. The pair faced off against each other in front of the Supreme Court in Bush v. Gore, but are now teaming up to try to convince the justices that Prop 8 and gay marriage bans in general are discriminatory. The attorneys have made the broader argument that the government has no reason to exclude people from marriage based on sexual orientation. Olson has 20 minutes to argue their case on Tuesday.
The Prop 8 defenders:
Dennis Hollingsworth, a former Republican state senator from the Temecula area, and other supporters of Proposition 8 took responsibility for defending the ban on gay marriage after the California attorney general declined to appeal the district court?s decision striking it down.
Hollingsworth is a leader of Protect Marriage, a group of supporters of Prop 8 who raise money for its legal defense now that the state has bowed out. The group says it is defending the millions of Californians who voted for Prop 8 from having their voices overruled by the courts.
Their attorney:
Charles Cooper, a former Justice Department official under President Ronald Reagan, has been the lead attorney for Proposition 8 since it was first challenged by gay marriage supporters. Hollingsworth reportedly chose Cooper because he thought his skills as an attorney were on par with Olson?s. Cooper has stressed in his briefs that the Supreme Court should not interfere with states? wishes on gay marriage and argues that the government has legitimate reasons to discourage same-sex couples from marrying. Cooper will have 30 minutes to make his arguments and answer the justices' questions on Tuesday.
Source: http://news.yahoo.com/blogs/ticket/prop-8-gay-marriage-case-085022722--election.html
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